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Powder Anastrozole
Best Price Powder Anastrozole
Name: Anastrozole(Arimidex) powder
CAS: 120511-73-1
Molecular Formula: C17H19N5
Molecular Weight: 293.37
Melt Point: 81-82°C
Storage Temp: RT
Color: White crystalline powder
Anastrozole powder is a non-steroidal aromatase-inhibiting drug approved for treatment of breascancer after surgery, as well as for metastasis in both pre and post-menopausal women.The severity of breast cancer can be increased by estrogen, as sex hormones cause hyperplasia, and differentiation at estrogen receptor sites. Arimidex powder works by inhibiting the synthesis of estrogen.
Items | Standard | Results |
Description | White crystalline powder | Complies |
Identification | IR HPLC Reactive | Conform with standard IR Conform with standard HPLC Conform |
Solubility | Freely soluble in methanol,acetone,ethanol and tetrahydrofuran.And very soluble in acetonitrile | Complies |
Total Impurity | max.0.5% | 0.18% |
Total Unspecified Impurity | max. 0.2% | 0.08% |
Individual unspecified impurlty | max. 0.1% | 0.05% |
Related compound B | max. 0.2% | 0.07% |
Related compound C | max. 0.2% | 0.04% |
Related compound D | max. 0.1% | 0.05% |
Related compound E | max. 0.1% | 0.06% |
Limit of cyclohexane | max. 0.08% | ND |
Limit of ethylacetate | max. 0.1% | 0.07% |
Melting point | 81.0~84.0°C | 82.5~83.2°C |
Water | max. 0.3% | 0.21% |
Residue on ignition | max. 0.1% | 0.07% |
Heavy Metals | max.0.001% | Complies |
Assay(HPLC) | 98.0%~102.0% | 99.8% |
Storage | Cool and dry | |
Conclusion | It complies to USP32 |
Steroids Raw Material Anastrozole powder is used to treat postmenopausal women with estrogen receptor positive breast cancer. This drug is often given in conjunction with other drugs such as tamoxifen in early stage cancers. Anastrozole powder is taken in tablet form usually just once a day. Common side effects include hot flashes, nausea, decreased energy, back and bone pain, joint pain or stiffness. Side effects may differ from those listed above if anastrazole is being taken with other medications.
Third generation aromatase inhibitors.A patient with advanced breast cancer after menopause.