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CAS 26095-59-0 Otilonium Bromide
CAS 26095-59-0 Otilonium Bromide
Octylonium Bromide has been reported to antagonize PAF (platelet-activating factor) induced aggregation of rabbit platelet-rich plasma, hypotension in rats, lethality in mice, and bronchoconstriction in guinea-pigs. This compound also demonstrates the ability to potently block neuronal nicotinic acetylcholine receptors and also a mild wide-spectrum Ca2+ channel blocker in bovine adrenal chromaffin cells. Additionally, Octylonium Bromide has been shown to inhibit muscular action potentials carried by L-type Ca2+ current. Octylonium Bromide is an inhibitor of PAF-R.
Item |
Requirements |
Description |
White to off- white crystalline powder |
Water |
≤0.20% |
Total impurities |
≤0.60% |
Other individual impurity |
≤0.10% |
Relative retention time at about 0.4 impurity |
≤0.30% |
Relative retention time at about 0.90 impurity |
≤0.20% |
Residual solvents |
≤0.3% |
Loss on drying |
≤0.50% |
Assay(On the anhydrous and solvent-free basis) |
98.0%~102.0% |