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Natural Peanut Shell Extract Powder 491-70-3
Product name: Luteolin
Synonym name: Digitoflavone; Daphneflavonol; Flavopurpol; Luteolol
Cas No.: 491-70-3
Formula: C15H10O6
Mol Weight: 286.239
Botanical Source: Peanut shell
Physical Description: Yellow powder
Type of Compound: Flavonoids
Luteolin is a naturally occurring molecule known as bioflavonoid, often found in foods including parsley, artichoke leaves, celery, peppers, olive oil, rosemary, lemons, peppermint, sage, thyme, and many others. Luteolin is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an agent in the prevention of inflammation, a promoter of carbohydrate metabolism, and an immune system modulator.
Ethanol reflux is a common method of extracting it from peanut hulls. This process essentially consists of mixing the powdered hulls with 70 percent ethanol to obtain a liquid/solid ratio of 20:1. This mixture is then heated at 85 degrees Celsius for at least 1.5 hours. The vapor that comes off the mixture is high in this substance, which can be further concentrated to a high level of purity.
Item | Specification | Result |
Physical control | ||
Appearance | Brown Powder | Complies |
Assay | 2.5% | 2.58% |
Odor | Characteristic | Complies |
Particle Size | 100% pass 80 mesh | Complies |
Loss on Drying | ≤5.0% | 3.25% |
Chemical Control | ||
Total Heavy Metals | ≤20ppm | Complies |
Ash | ≤1ppm | Complies |
Lead | ≤1ppm | Complies |
Arsenic | ≤1ppm | Complies |
Residue of Pesticide | Complies | |
Microbiological Tests | ||
Total Plate Count | ≤1000cfu/g | Complies |
Yeast&Mold | ≤100cfu/g | Complies |
E.coil | Negative | Complies |
Salmonella | Negativev | Complies |
Staphylococcus | Negative | Complies |
1, Anti-inflammatory, antioxidant and free radical scavenger. Inhibits LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocks NF-κB and AP-1 activation.
2, Also inhibits TNF-α -induced COX-2 expression. Antiproliferative and chemopreventative; inhibits proliferation of Lewis lung carcinoma cells in vivo.
3, Luteolin, is a common flavonoid, has anti-oxidant, anti-inflammation, anti-allergy and anticancer, has been used in Chinese traditional medicine for treating various diseases such as hypertension, inflammatory disorders, and cancer.
4, It can reduce production of proinflammatory mediators and inhibit LPS-induced IL-6 production in the brain by inhibiting the JNK signaling pathway and activation of AP-1 in microglia, also shows potent anti-inflammatory activities by inhibiting nuclear factor kappa B (NFkB) signaling in immune cells, thus, could be a promising candidate to develop immuno-modulatory and neuroprotective therapies for the treatment of neurodegenerative disorders.
5, This extract induces apoptosis in various cancer cells, one mechanism through death receptor 5 (DR5) upregulation, its treatment might be promising as a new therapy against cancer.
6, It attenuates TGF-β1-induced epithelial–mesenchymal transition of lung cancer cells by interfering in the PI3K/Akt–NF-κB–Snail pathway, strengthen the anti-cancer effects of flavonoid compounds via the regulation of migration/invasion and EMT ability of various cancer cells.
1). Applied in food field, Luteolin is often used as food additives;
2). Applied in health product field, Luteolin is made into capsules with the function of vasodilatation;
3). Applied in pharmaceutical field, Luteolin can play the role of inflammation;
4). Applied in cosmetic field, Luteolin is often made into the products of losing weight.
Shipping Terms | ||
By Express | By Air | By Sea |
Suitable for under 10KG Fast : 3-5 day High cost Door to door service Picking up goods easily |
Suitable for under 50KG Fast : 5-7 day High cost Port to port Professional broker needed |
Suitable for large quantity Slow : 7-45 day Low cost Port to port Professional broker needed |