What's the differences between NMN, NR, NAD?
NMN bypasses the bottleneck of the NAMPT rate-limiting enzyme and can quickly replenish NAD+ in the body, which is the best and ideal supplement method. NMN can quickly enter the blood within 10 minutes, and after 30 minutes it is absorbed by the organs of the body and converted into NAD+, which can quickly replenish NAD+ in the body.
Most of the oral NR is not converted into NMN, but is digested into NAM, failing to bypass the restriction of the rate-limiting enzyme NAMPT in the salvage synthesis pathway, and the ability to supplement NAD+ is limited.
NAD+ is an important coenzyme in the mitochondria for aerobic oxidation and metabolism of tricarboxylic acid cycle to generate energy molecular ATP, so that the three types of nutrients obtained by the human body: sugar, fat and protein, are transformed into the energy required by the human body. However, due to its large molecular weight, it is difficult for NAD+ to penetrate the cell membrane and enter the cell, so it cannot be directly taken up.